Holmes' first experience with crack cocaine was when she smoked with her mother at the age of 12. She dropped out of school in the 10th grade. After leaving school, she moved to New York City to live with her boyfriend Ilya Leontyev. The two fell into heavy drug and alcohol abuse, with Holmes first trying heroin at the age of 17. She was largely homeless for the next three years. Leontyev died of an overdose in Central Park in April 2015.
创作上情节的真实无序(一切按照事件可能会发生的逻辑随机出现而不是围绕剧本要传达的某个意义)和角色真实外延(真正的毒虫也是unpredictable)相映成辉，完全的新浪潮风格，摄影和调度也有很多大胆/复古尝试，比如隔着火苗的长焦镜头表现烧人，大量的特写。
影片之外来说，毒虫就是极度自私和极简社会关系，而这恰好就是每个人的真实自我，或许这就是观众感动的原因，因为他们侧面看到了他们被社会扭曲的、从幼时就存有的关于自杀、偷窃、强暴/胁迫、欺骗的内心深处。
另外
开篇便是逐渐紧张的电子鼓点，迷幻电音融入街头流浪的生活，是一种气氛，也是一种形象化的糜烂生活般的快感和虚无。
哈莉对伊利亚说“如果我死掉，你会原谅我吗？”她便去买了五毛钱的刀片准备割腕，她爱他，哪怕为他失去生命也愿意。当鲜血喷涌而出，伊利亚还是救了哈莉。他们之间的爱情是病态的相互折磨，窒息毁灭性的存在，两个堕落虚无又厌世的人，游荡在纽约街头城市各个角落。
萨弗迪兄弟一如既往的写实风格，手持运动镜头，只不过更加成熟内敛
天知道：轻松打破观众对瘾君子的刻板单调印象
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